The report says there were a total of six confirmed hospital cases of the bacterium during the outbreak between Dec. 21 and Feb. 3.
Two of those patients died, but the cause of death in both cases is still under review.
The report says the hospital needs to strengthen infection control practices.
Earlier in 2011, 64 patients in seven of the Cape Breton Regional Health Authority's nine hospitals were affected by an outbreak of C. difficile that lasted several months.
A report on that outbreak by the Public Health Agency of Canada made a number of recommendations ranging from hospital renovations to reducing patient transfers.