The two-year agreement is aimed at retaining and recruiting nurses, especially in rural and northern communities.
The Saskatchewan Union of Nurses and the province first signed a partnership agreement in 2008 to hire 800 more nurses over four years and reached that goal.
The latest agreement doesn't have a specific target.
Health Minister Dustin Duncan says the shortage of nurses is not a critical as it once was, but there are other issues that still need to be addressed.
He says the number of nurses nearing retirement could pose a challenge going forward.