Clinton will meet President Thein Sein in Siem Reap, Cambodia, on Friday. Together they will participate in a forum aimed at bringing investment to Southeast Asia.
The events come after the Obama administration granted permission Wednesday for American companies to invest in the country also known as Burma, and work with its state oil and gas enterprise. That action was a reward for a series of reforms by Myanmar's government.
Clinton previously met with Thein Sein when she visited Myanmar last year. That was the first trip by a U.S. secretary of state to the country in more than 50 years.