The bridge will have one lane open in each direction from Sunday, July 22 at 2 a.m. to Tuesday, July 24 at 8 a.m.
Lane closures are also scheduled for Saturday, July 28 at 2 a.m. to Monday, July 30, at 8 a.m.
The bridge bike path remains open during these closures.
The bridge will be repaved during this round of road work.
Alternate routes to the South Shore include the Champlain, Mercier and Victoria Bridges.