Most gathered at homes to watch their two top male sprinters in the head-to-head showdown. If the weather is clear, fans are expected to submerge the national stadium in a sea of green, gold and black — the country's colours — to watch the race on big video screens.
The Caribbean island is a hothouse for producing sprinters and for weeks, Jamaicans have been enthusiastically debating whether Bolt or Blake will claim top honours. The rest of the field, including Americans Tyson Gay, Justin Gatlin and another Jamaican, Asafa Powell, are barely getting a mention.
"Bolt all the way! The big man a go defend it! Blake have to settle for silver," Bernard Wolfe shouted in Jamaican patois to neighbourhood buddies who were rooting for Blake in the Kingston community of Grant's Pen.
Blake, Bolt's countryman, workout partner and blisteringly fast rival, beat the Jamaican sensation in the 100- and 200-meter finals during the island's Olympic trials. Bolt's subsequent withdrawal from a meet in Monaco only added to the intrigue and set up the most anticipated storyline of the 2012 Games.
Jamaica is already in a party mood. It's celebrating its 50th anniversary of independence on Monday. Plus, Shelly-Ann Fraser-Pryce has made it back-to-back Olympic titles in the women's 100 metres, an exciting way to start a historic weekend in Jamaica, which became independent of Britain in 1962.
A one-two by Bolt and Blake would be the icing on the cake in Jamaica, a high-spirited tropical island with a chronically sputtering economy.
The expectations are very high for Bolt, the 6-foot-5 sprinter with huge, loping strides who has repeatedly said he is seeking gold at the London Olympics in order to become a sporting legend.
He's been the country's biggest living icon almost from the moment he kicked off the Jamaican medals haul in Beijing at the 2008 Olympics with his world-record time of 9.69. He earned that record even after he lost time by mugging for the cameras with about 20 metres to go, stretching his arms out with palms up, then pounding his chest.
Bolt went on to win three gold medals and set three world records in the last Olympics, a staggering achievement.
This time around, the charismatic Bolt may be the favourite to win, but Blake poses a serious challenge.
The muscular sprinter nicknamed "The Beast" has a relentless devotion to training that has made him a huge star in his homeland. He's not intimidated by Bolt, who is some six inches taller.
"I'm hungry for a medal," Blake told reporters recently.