Manager John Farrell says the slugger had six at-bats Wednesday morning in a simulated game. He'll be in the lineup with Double-A New Hampshire on Thursday before joining the Blue Jays at Baltimore a day later.
Bautista hasn't played since July 16 because of a left wrist injury. He's hitting .244 with 27 homers on the year.
Before Wednesday night's game at Detroit, Toronto put shortstop Yunel Escobar on the paternity list and recalled right-hander Chad Beck from Triple-A Las Vegas.