Three members of a Quebec family, including a two-month-old girl, were killed in an early morning crash today on Highway 401 west of Iroquois, about 100 kilometres south of Ottawa.

Ontario Provincial Police said a tractor-trailer and a van collided near the turnoff to Highway 416 at about 1 a.m. ET Monday.

Pronounced dead at the scene were the three of the van occupants, all from Chateauguay, Que.:

- Elissa Reid, 22.

- Moriah Gloria Warren, Reid's two-month-old daughter.

- Sheila McGlashen, 78, Reid's grandmother.

Three other family members in the van — Reid's father, mother and brother — were transported to Winchester Hospital and subsequently to the Civic Hospital in Ottawa with serious but non-life-threatening injuries.

The driver of the tractor-trailer was treated at Cornwall Community Hospital for minor injuries and has since been released.

Police said a fire erupted in the tractor-trailer after the collision and spread to the van.

It took crews several hours to remove the tractor-trailer from the scene.

Highway 401 westbound lanes opened to traffic at 9:30 a.m. One lane of Highway 401 eastbound remains closed.

Ontario Provincial Police officers remain at the scene and continue to investigate.