Huot won Canada's first medal of the Games — a gold — in world record time in the 200-metre individual medley.
He added a silver in the 400 freestyle and bronze in the 100 backstroke.
In four Paralympic Games, Huot has won 19 medals, including nine gold. He was thrilled over being chosen to lead Team Canada at the closing ceremony.
"I would say it's by far the greatest honor that I can receive as an athlete," Huot said. "It's going to be an amazing time and I'm going to stand up and carry the flag as high as I can, and be proud of it."
Canadian athletes have 30 medals at the Games, including the gold medal in wheel chair basketball won Saturday night.