He will make an announcement with Oceans North Canada and the Qikiqtani Inuit Association on behalf of his foundation, which supports environmental conservation projects.
Chris Debicki is the projects director with Oceans North Canada.
"It's a very exciting moment. He and his foundation are big supporters of marine conservation projects around the world and we're very happy that they've agreed to come and visit and will continue to support local initiatives in Nunavut."
The prince is scheduled to meet with Premier Eva Aariak, Iqaluit Mayor Madeleine Redfern and students at Nunavut Arctic College.
He is scheduled to leave Nunavut's capital on Friday.
His visit comes a week after a visit from Prince Edward and his wife, Sophie Rhys-Jones, the Earl and Countess of Wessex.