Premier Pauline Marois met with Grand Chief of the Grand Council of the Cree, Matthew Coon Come, Monday for the first time since taking office in September.
Coon Come introduced Marois as a "friend of the Cree people," and underlined the work she did during the Paix des Braves.
"She was the minister of finance then, she's very familiar with the intent, the spirit of Paix des Braves," said Coon Come.
"We will build upon that relationship... with the government of Quebec that is based on nation-to-nation," he said.
The Paix des Braves is an agreement signed in 2002 by former Parti Québécois minister Bernard Landry and Ted Moses, the former Cree chief. At the time, the Cree agreed to drop a multitude of lawsuits against the government in exchange for $4.5 billion in funding over a period of 50 years.
In July 2012, former Quebec premier Jean Charest introduced plans for the regional government.
Marois said the community would play a role in the decisions regarding development of the province's north.
The renewed agreement gives the Cree more autonomy and control over the economic development of their region.
Both politicians met before the news conference to discuss whether the province would put a moratorium on uranium mining. The Cree are opposed to a proposed uranium mine project in their region.
Marois said her government would make its position known in coming weeks.