Natural Resources Canada says the 4.2-magnitude quake hit just before 3 a.m. ET just east of Matane on the GaspéPeninsula.
Provincial police received several 911 calls following the quake, but no damage was reported. The rumbling was reportedly felt as far away as Ste-Anne-des-Monts, about 90 kilometres east.
Quebec has experienced several small earthquakes in the past few months, several of which were powerful enough to cause some rattling.
On Oct. 10, thousands of people called 911 in and around Montreal after a 4.5-magnitude quake struck near Saint-Hyacinthe.
A month later, a 4.2-magnitude earthquake shook the Gatineau region.
Every year, about 200 small earthquakes occur in the Western Quebec Seismic Zone, roughly located in the area between Montreal and Ottawa.
Most of those quakes are small enough that they go unnoticed.