James (10-16) and Wade (11-13) made 21 of 29 shots for Miami, which shot 58 per cent overall to improve to 10-1 at home this season. Chris Bosh had 14 points and 10 rebounds, and Norris Cole scored 10 for the Heat, who handed the Hawks only their second loss in 11 games.
Josh Smith scored 22 points and Al Horford finished with 20 points and 11 rebounds for Atlanta, which briefly held the lead midway through the third quarter before the Heat got rolling and moved 1 1/2 games ahead of the Hawks in the Southeast Division.
Atlanta is 0-2 against Miami this season and 1-7 since March 2011.
A 17-4 run was the difference maker, turning a two-point deficit into an 11-point lead with 1:24 remaining in the third. Wade got it started with a jumper, and he wound up with eight points during the burst, including a layup off a perfect pass by James from the right side of the lane.
SPURS 134, ROCKETS 126, OT
HOUSTON (AP) — Gary Neal hit seven 3-pointers and scored 29 points, and Tony Parker had a triple-double with 27 points, 12 rebounds and 12 assists to lead San Antonio over Houston.
Jeremy Lin had his best game since joining the Rockets, scoring a career high-tying 38 points with leading scorer James Harden sidelined by a sprained right ankle.
Neal's last 3-pointer followed by a three-point play by Manu Ginobili put the Spurs ahead 130-122 with two minutes left in overtime, and they held on for the win. It was San Antonio's fifth straight win overall and second over Houston in three days after a 114-92 victory Friday.
Houston is 0-2 since coach Kevin McHale returned to the bench following the death of his daughter.
WARRIORS 104, BOBCATS 96
CHARLOTTE, N.C. (AP) — Stephen Curry put on a show for his hometown fans, finishing with 27 points, seven assists and seven rebounds to lead Golden State over Charlotte.
Curry, who grew up in Charlotte and made a name for himself leading nearby Davidson College to the brink of the Final Four in 2008, shot 10 of 22 from the field and hit four 3-pointers. It was his eighth straight 20-point game, a career best.
David Lee had 25 points and 11 rebounds for the Warriors (14-7), who have won seven of their past eight games and improved to 4-0 on their current seven-game Eastern trip.
Kemba Walker scored 24 points to lead the Bobcats, who have lost eight straight.
MAVERICKS 119, KINGS 96
DALLAS (AP) — O.J. Mayo scored 19 points and Dallas took control with a 31-3 run in the first half to beat Sacramento for the 17th straight time at home during the regular season.
Chris Kaman, playing on a sprained left ankle he suffered last week, scored 16 of his 18 points in the first half for Dallas.
Francisco Garcia, who was 7 of 12 from 3-point range, and DeMarcus Cousins scored 25 points apiece for the Kings, who haven't won in Dallas during the regular season since Feb. 27, 2003.
Mayo hit a jumper late in the first quarter to kick off the game-turning run for the Mavs, who led by as many as 28 in the first half and were up 65-43 at halftime.
TRAIL BLAZERS 92, RAPTORS 74
PORTLAND, Ore. (AP) — LaMarcus Aldridge had 30 points and 12 rebounds to lead Portland to a win over Toronto in a game that was overshadowed by injuries for both sides.
J.J. Hickson added 16 points and 11 rebounds for the Trail Blazers, who were without injured starters Nicolas Batum and Wesley Matthews.
DeMar DeRozan scored 20 points for the Raptors, who lost forward Andrea Bargnani to a right elbow injury and guard Kyle Lowry to a right shoulder problem during the game.
Toronto also lost reserve Amir Johnson in the second half after he was ejected for arguing with an official. Johnson threw his mouthpiece and had to be restrained by teammates before exiting.
76ERS 104, PISTONS 97
PHILADELPHIA (AP) — Evan Turner had 18 points and 11 rebounds, and Jrue Holiday scored 25 points to lead Philadelphia past Detroit.
Thaddeus Young added 20 points and Spencer Hawes had 15 for the Sixers.
Greg Monroe missed a tip-in with less than a minute left that came back to haunt Detroit. Holiday sank a 19-footer for a 100-95 lead and the Sixers stretched it from there at the free throw line.
Monroe and Brandon Knight had 22 points apiece. Rodney Stuckey scored 19 for Detroit, and Tayshaun Prince finished with 16.
Jason Richardson scored 13 points for Philadelphia.