The agency says sales were up 0.5 per cent in volume terms.
Five of seven subsectors, accounting for about two-thirds of wholesale sales, reported increases in November.
The largest advance in dollar terms was in the machinery, equipment and supplies subsector, which grew by 1.8 per cent on higher sales in the computer and communications equipment and supplies industry.
The motor vehicle and parts subsector recorded its second consecutive increase, with sales up 1.5 per cent.
Sales rose in Ontario, Manitoba and Alberta in November, with Ontario wholesalers reporting a 2.1 per cent increase, largest gain since July 2011.