Crosby, the leading scorer in the NHL, was struck in the face by a deflected slap shot from teammate Brooks Orpik just 1:28 into the game against the New York Islanders.
The Penguins said Crosby needed "major dental work" and will have more done in the coming days.
Penguins coach Dan Bylsma didn't rule out the possibility Crosby would undergo evaluation for a concussion, although there are no indications Crosby is suffering from concussion-symptoms.
"I think every time that type of thing happens to a player you think of that," Bylsma said. "It doesn't matter who it is. ... You think about those things regardless of the player, yes."
The incident also overshadowed the Penguins debut of Jarome Iginla, who said Penguins players were asking about the condition of their captain during the game.
"Very tough," Iginla said. "Very unfortunate play. Seeing on the replay, he didn't see it coming at all."
Pittsburgh won the game against the Islanders 2-0, running their win streak to 15 straight games. They next play Buffalo on Tuesday.