The Ubisoft title landed six awards on Saturday in Vancouver, including game of the year, the fans' choice award, and best animation.
"Mass Effect 3" from Bioware nabbed three trophies, including best console game.
"Mark of the Ninja," "Assassin's Creed III" and "Sound Shapes" each won two awards.
Meanwhile, best social/casual game went to "The Secret World" by Funcom Games/Electronic Arts.
And best game on the go went to "Sound Shapes" by Queasy Games/Sony Computer Entertainment.
A two-hour special of the Canadian Videogame Awards is scheduled to air on Citytv on Saturday and on G4 Canada on Sunday.