The Pacific Alliance was formed by Chile, Colombia, Mexico and Peru in 2011 and Canada took a spot on the sidelines the next year, along with several other countries as observers.
This week, alliance leaders will meet in Cali, Colombia, and be joined by Prime Minister Stephen Harper, as well as leaders from other observer nations.
"This will be the first time the prime minister has had the opportunity to participate in this forum, to experience the forum, to see what it has to offer," said Andrew MacDougall, a spokesman for the prime minister.
The goal of the nascent alliance is to tear down what economic borders remain between their countries, creating an integrated market to rival and compete both internationally and regionally with that of Mercosur, the trading bloc created in 1991 by Argentina, Brazil, Paraguay and Uruguay.
Alliance countries are already an economic powerhouse: according to the World Trade Organization, together they exported about $534 billion in 2011, compared to about $355 billion from Mercosur.
Bilateral merchandise trade between Canada and the four alliance countries totalled $39 billion in 2012, compared with $9.7 billion the year before in trade with Mercosur.
The Conservative government declared a stronger relationship with the Americas as a foreign policy priority in 2007 and has been wooing them ever since, ramping up its enthusiasm for ties with the region since its economies sailed through the global economic downturn in 2008.
But Canada already has free trade agreements with all four alliance countries and is involved in negotiations for the much broader Trans Pacific Partnership, which includes them as well as Asian countries, New Zealand and the United States.
That's raised questions about why joining this new alliance is something that Canada needs and has the resources to tackle.
Even pro-trade Tories raised this question at recent hearings on the alliance in the House of Commons.
"Where I'm coming from is that we already have relationships with all of these countries," said Tory MP Ed Holder in March.
"We don't need to do this, but maybe we do. What I'm looking for is the argument for Canada to do more than just sit at the table and watch."
Harper's participation in the meeting is about figuring that out, said MacDougall.
"From our perspective, there is no point picking one over the other, it's a question of pursuing on all avenues and all fronts," MacDougall said.
"We do have strong relationships with the four original members, and with some of the other observer countries so it makes sense for us to explore more ways to further strengthen that relationship while we're also pressing on the Trans Pacific Partnership, which includes another set of countries."
Among the issues being explored by the alliance are the removal of visa requirements for is members, something that would pose a challenge to Canada's ongoing efforts to tighten up borders by imposing visa restrictions on many countries, including those in the alliance.
The alliance also wants to strengthen security co-operation.
Canada has tried this once before with Mexico, in the form of the security and prosperity partnership with the United States, a deal that collapsed in 2009 to be replaced by the bilateral Beyond the Border plan with just the United States.
Canada's relationship with the Americas has been framed mostly in economic terms, though Canada insists part of its Americas strategy is also increasing democratic governance and security in the region.
Some observers have said those two planks aren't getting the same attention.
"The record of action to date has been narrowly focused on free trade agreements and the protection of corporate interests and investments at the expense of deep engagement on such important issues as development, security, corporate accountability, democratic governance, and human rights," Sheila Katz of the Canadian Council for International Co-operation told the House of Commons committee in April.
For example, as part of a recently-signed free trade deal with Colombia, the two countries agreed to table reports about the effect the deal has on human rights.
The second such report was May 15, 2013 due last week but since the House of Commons wasn't sitting, it couldn't be tabled, MacDougall said.
It's unlikely to appear before Harper returns from his trip.
Prior to arriving in Colombia, he will travel to Peru for bilateral meetings with that country's president.