The low-level sprayings will happen on Thursday and Friday, weather permitting.
"Infestation levels reached a point where manual control methods such as egg scraping, sticky traps, and ground spraying of pesticides are no longer effective in controlling the Gypsy Moth population," said a statement from the city.
Areas of Etobicoke will be targetted on Thursday:
- Humber Valley Golf Course
- Valecrest Road and North Drive
- The Kingsway — Edenbridge Drive
- Thorncrest Road
- Herne Hill
- Princess Margaret Boulevard — Kipling Avenue
- Royal York Road and The Kingsway
On Friday the spraying will shift to the east:
- Moore Park
- Cherry Beach Park
- Toronto Island Park
- Tam O'Shanter Golf Course
The spraying will take place between 5 and 7 a.m., both days.
The pesticide being used "is not considered a health risk to humans," the city said.
Residents within the affected spray zones are encouraged to check for updates on the City's website at or by calling 311 (1-855-551-5150 if calling from outside Toronto).