RCMP say they got a call Wednesday about the foursome who had gone canoeing four days earlier on the Christina River south of Janvier.
Search patrols found two of the men on an island in the river and they were rescued by a military helicopter a few hours later.
The two, who are 67 and 59, were treated at the scene for minor injuries.
"They had been on the island for two days with no supplies — lots of water — no food or other resources and the bugs were pretty bad," RCMP Supt. Bob Couture said Thursday.
"A little hypothermic, but they sound to be OK.
Police say an air search continues for the two other men.
Authorities are warning people to stay away from rising and rushing rivers in the area.
(CFVR, The Canadian Press)