The incident occurred around 11:30 p.m. PT at Ballenas Court and Gabriola Drive, near Coquitlam River Park.
A short distance away, near the Lougheed mall, police recovered a vehicle they say may be connected to the shooting.
The man and woman were taken to hospital with gunshot wounds and police say they are in stable condition.
While police suspect it was a targeted and drug-related shooting, RCMP Cpl. Jamie Chung said they have no reason to think it was gang-related.