HBO and Gandolfini's managers confirmed his death Wednesday night, saying it was believed the actor died of a heart attack.
"Our hearts are shattered and we will miss him deeply. He and his family were part of our family for many years and we are all grieving", his managers Mark Armstrong and Nancy Sanders told Deadline.com.
The show, which spanned six seasons, followed Soprano's struggles to deal with his family and work life while talking it out with his therapist.
Gandolfini's long acting career had several highlights. We've picked a few scenes from some of his best roles. You can view them below.
The Man Who Wasn't There (2001)
In The Loop (2009)
The Sopranos (1999 - 2007)
Twitter fans came out in droves to remember Gandolfini, calling him "one hell of an actor" and "responsible for one of the greatest characters, ever."