Heavy smoke is the main concern for officials. The fire, which started earlier in the week, is across Lake Athabasca from the town, but thick black smoke is drifting into the community.
Crews plan to move 200 people considered high risk — infants, pregnant women, the elderly — to safer ground.
RCMP said Saturday that they were working on moving the first 110 people. Many may need to be flown out.
Provincial fire crews were using aerial tankers to try and keep the fire under control.
If it escalates, officials said the entire town may need to be evacuated.
About 1,000 people live in Fond-du-Lac.