They say they're concerned for the safety of Ernest Kirkland, 82, and Marilyn Kirkland, 69.
Ernest is described as 5 foot 7, with a medium build and a shaved head. He walks with a cane.
Marilyn is described as 5 foot 9 and 160 pounds. She has shoulder-length, grey-brown hair.
They were last spoken to on Monday, July 22.
Anyone with information is asked to contact police at 416-808-5500 or Crime Stoppers at 416-222-TIPS (8477).