Mark Trumbo hit a three-run homer and Mike Trout also went deep against Mark Buehrle, helping the Angels build a 5-2 lead for C.J. Wilson. But the Blue Jays rallied with two in the eighth, as Angels manager Mike Scioscia used five pitchers to get out of the inning — including Wilson and Frieri, who was called upon to attempt a four-out save.
Frieri (0-4) ended the eighth by catching Colby Rasmus' popup in front of the mound, but gave up a single by Brett Lawrie and plunked No. 9 hitter J.P Arencibia to open the ninth.
The Angels then caught Lawrie straying off second, and it looked like they had him tagged out in a rundown with Jose Reyes batting. But second base umpire Brian Knight called Lawrie safe diving back to the bag, provoking an argument by Scioscia and second baseman Erick Aybar.
Frieri then retired Reyes on a flyout before De La Rosa came in and got Rajai Davis to hit a fielder's choice grounder. But Bautista and Encarnacion spoiled the right-hander's bid for his first major-league save with ground singles to left field.
Brett Cecil (5-1) got two outs to earn the victory and Casey Janssen retired the side in order in the ninth for his 19th save in 21 chances.
Buehrle allowed five runs, seven hits and two walks in six innings, becoming the only Blue Jays starter in the series to get past the fifth after Josh Johnson, Todd Redmond and Esmil Rogers combined to give up 17 runs and 27 hits in 11 innings. Buehrle's scoreless streak ended at 20 innings when Trout homered to left-centre in the first.
Wilson was charged with four runs — three earned — and eight hits in 7 1-3 innings, struck out seven and walked none.
The Angels pulled ahead 5-2 in the fourth with a four-run rally, marking the sixth time during this series that they scored three or more runs in an inning.
Trout drew a leadoff walk and Howie Kendrick singled before Trumbo drove an 0-2 pitch into the lower seats in the left field corner, becoming the eighth player in Angels history to hit at least 25 home runs in three consecutive seasons. One out later, Buehrle gave up consecutive doubles by Aybar and Chris Iannetta.
The Blue Jays took a 2-1 lead in the third with four straight two-out singles, including run-scoring hits by Davis and Bautista. Both runs were earned despite two throwing errors — one by third baseman Chris Nelson after he charged in to barehand Reyes' bunt hit, the other by first baseman Trumbo when he tied to get Davis at second after Wilson picked him off. Davis was credited with a stolen base.
NOTES: The Angels signed 31-year-old LHP Dontrelle Willis to a minor league contract and assigned him to Triple-A Salt Lake. The two-time All-Star and 2003 NL rookie of the year hasn't appeared in a major league game since Sept. 25, 2011 with Cincinnati. He was pitching this season for the Long Island Ducks of the independent Atlantic League and started in their All-Star game. ... The only other time Buehrle and Wilson started in the same game was April 27, 2010, when Wilson got the win and Buehrle took the loss in the Texas Rangers' 4-2 victory over the Chicago White Sox. ... The Angels have committed 83 errors, tying Milwaukee for the major league lead. ... Davis stole third in the eighth inning to raise his season total to 33, second in the AL behind Jacoby Ellsbury's 40. ... Buehrle is 48-50 with a 4.05 ERA in 131 starts since his perfect game against Tampa Bay on July 23, 2009. ... Angels LHP Jason Vargas came out of Saturday's simulated game with no complications, and is scheduled for a five-inning minor league rehab start next Thursday. ... Izturis, who spent the previous eight seasons with the Angels before signing a three-year, $10 million contract with the Blue Jays in November as a free agent, was 2 for 11 with a walk in his first series against his former club. ... Buehrle is 2-6 with a 5.90 ERA in his 11 road starts this season. The only wins came against the top two teams in the AL West — Oakland and Texas. ... Buehrle has made 419 big league starts without ever going on the disabled list — the longest such streak among active players.