RCMP say some of the people who were inside the van Friday morning near the Buffalo Lake Metis Settlement fled the accident scene.
At least one person told someone who lived nearby that there was a critically injured woman inside the van.
She was pronounced dead by emergency crews.
An injured 16-year-old youth was found in another nearby home and he was flown to an Edmonton hospital by helicopter in stable condition.
Police believe alcohol and speed were factors in the crash and that none of the people inside the van were wearing seatbelts.
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