Police were dispatched to the scene on King Street West, near the King-Spadina intersection, just after 2 a.m. ET on Friday.
Police said that a dispute between a group of men took place inside the nightclub and during the incident multiple shots were fired, injuring the bouncer.
The bouncer, and a second man who suffered injuries to his head, were taken to a local hospital.
Mohamed Salim, 28, of Toronto, is facing eight charges including attempted murder, possession of an unauthorized firearm and breach of recognizance.
Abdiweli Abdi, 25, is charged with assault with a weapon and weapons dangerous.
Both men appeared in court on Friday.