The East Nepean Eagles advanced to the annual tournament in Williamsport, Pa., on the weekend after winning the Canadian championships against a team from British Columbia.
The 16-team tournament features eight teams from the U.S. and eight international squads.
East Nepean last played in the tournament in 2004, when they were eliminated in the group stage after losing two of their three games.
They play Chung-Ping Little League, this year's representative from Taiwan, at 1 p.m. ET Friday.
Teams from Taiwan have won 17 little league championships, but the last one was in 1996.
Canada's next game will be either Saturday or Sunday, depending on the outcome of Friday's game.