Assistant Commissioner Russ Mirasty is retiring at the end of the month.
Mirasty became the first First Nations person to lead an RCMP division when he took the post in December 2010.
He will be replaced by Chief Superintendent Brenda Butterworth-Carr, who becomes the first female aboriginal commanding officer.
Butterworth-Carr joined the RCMP in 1987 as a native special constable.
She has served in Yukon, British Columbia and Saskatchewan in many key positions including as the First Nations policing co-ordinator.
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