Police say a white panel van caught fire after it crashed into a concrete wall at 53rd and Oak streets in Vancouver around 3 p.m. PT. Monday afternoon.
Police initially said there was equipment or chemicals for a meth lab in the van, but just before 5 p.m., police released a statement saying this could no longer be confirmed.
Officers and a police dog are now searching the area for two men who fled the scene.
During the crash, another vehicle was struck and police say two occupants of that car have been taken to hospital with unknown injuries.
Police have closed the area and dispatched a hazardous materials team. They're asking commuters to avoid Oak Street between 54th and 57th.
The area is expected to stay closed as police and fire officials investigate the crash.