Organizers are anticipating approximately 25,000 runners from over 60 countries to descend on the city to run and raise money for local charities such as Autism Dog services, St. Christopher House and Engineers Without Borders Canada. They are also estimating that 150,000 spectators will be cheering on the runners from the sidelines.
A total of 35 Streets from High Park to the Beaches will begin shutting down at noon on Saturday and will reopen Sunday evening.
In 2012 the marathon raised more than $4 million for more than 180 charities across Canada.
The full race course begins at University Avenue and Dundas Street West and will loop around High Park and out to the Beaches.
Neighbourhood cheering centres have been set up around the city to watch the race, however a team of judges will determine which centre has the most spirit and the best entertainment. The winning centre will be rewarded $6,000, $3,000, $2,000, or $1,000 for their charity.
The marathon has said that they have been working with the city, Toronto police, TTC and city councillors to bring the event to the city with the least amount of disruptions.