The Calgary-based junior energy company says Encana has agreed to a three-year lease covering 38,757 hectares in the Entice area.
Manitok will have a 100 per cent working interest in the leases, which are contiguous with its core areas.
It has committed to spend $106 million over the period, including $22 million in 2014.
Manitok also announced Monday that a syndicate of underwriters initially agreed to acquire $20 million worth of flow-through shares from the company, and then increased the bought-deal was to $25 million later in the morning.
It said proceeds from the equity sale will be used by Manitok for exploration on its Canadian properties prior to Dec, 31, 2014. The flow-through shares allow investors to receive tax credits for eligible spending by the company.