Police said they received a 911 call at about 3:20 a.m. reporting a man was lying on the ground on St-Laurent Boulevard near the Sauriol Street intersection.
According to police, witnesses said they saw the man being attacked by at least four people.
The victim was rushed to the hospital with at least one stab wound in his upper body.
Police said he is in critical condition.
St-Laurent Boulevard is closed northbound between Fleury and Sauriol for the police investigation.
The victim's identity has not been released.