The Ontario Provincial Police say that a Mazda MPV was heading northbound when the collision occurred just north of Sheppard Avenue, at about 4:20 p.m.
The van’s driver and passenger were transported to a Toronto hospital.
Hours later, the OPP tweeted that the 60-year-old male passenger had died.
Police say the driver of the truck wasn't hurt in the crash.
The collision remains under investigation.