The result was a franchise record for one of the NFL's best wide receivers, and a big win for the Detroit Lions.
Johnson caught a 14-yard touchdown pass from Stafford with 2:22 to go, helping the Lions edge Jay Cutler and the Chicago Bears 21-19 on Sunday in a key matchup of NFC North rivals.
"I knew immediately that one of us on the outside was going to get it," Johnson said. "So I just wanted to work, be patient and he threw a great ball."
Johnson also had a tiebreaking TD reception in the third quarter and Reggie Bush rushed for 105 yards as Detroit (6-3) swept the season series against Chicago (5-4) for the first time since the 2007 season.
When Green Bay lost 27-13 to Philadelphia, the Lions were all alone in first in the division for the first time since the end of Week 5 of the 2005 season, according to STATS.
"We came out with a victory on the road against a really tough team," Detroit coach Jim Schwartz said. "It was a hard-fought win. Proud of the players, but that's the only thing that means (anything) today.
"I mean first place, you don't get any prizes for first place there nine games into the season."
Johnson's ninth touchdown grab of the season was the 63rd of his career, breaking a tie with Herman Moore for the Detroit record. Moore still leads with 670 career receptions for the Lions, but Johnson might take that record down at some point, too.
"To be a part of history for the Lions, that's a big deal," Johnson said.
Johnson, playing in his 100th game, has 8,740 yards receiving, the second-most in NFL history in a player's first 100 games. Johnson trails Hall of Famer Lance Alworth who had 9,019.
Cutler threw for 250 yards and a touchdown in his first action since he injured his groin last month. He injured his left ankle in the second quarter and looked progressively worse as the game wore on.
Coach Marc Trestman finally decided to put in Josh McCown before the Bears' final drive.
"I didn't want to take him out unless he felt he couldn't do the job," Trestman said. "It was, I thought, a very courageous performance throughout. Then at the end I took him out because I knew he would have to run around in the two-minute drill and that's when we decided to put Josh in the game."
McCown drove the Bears down the field, throwing an 11-yard touchdown pass to Brandon Marshall with 40 seconds left.
After a roughing penalty on Willie Young gave the Bears another chance at the tying 2-point conversion, Nick Fairley threw Matt Forte down in the backfield to preserve the win for Detroit.
"I just figured it would be a run or a play-action pass," Fairley said. "I just scouted out the ball real good and it was just happy I made the play."
Stafford threw for 219 yards for Detroit, which has won two in a row for the first time since the end of September. Johnson had six catches for 83 yards.
The Lions were clinging to a 14-10 lead when Chris Conte intercepted an overthrown ball by Stafford and returned it 35 yards to the Detroit 9.
Forte then had a touchdown run negated by a holding penalty on left guard Matt Slauson and an apparent scoring pass to Alshon Jeffery was overturned when a replay showed he lost control of the ball when he hit the ground.
Robbie Gould's 32-yard field goal trimmed the Lions' lead to one with 9:17 remaining, setting the stage for the frantic finish.
It was Cutler's first game since he was sacked by Redskins nose tackle Chris Baker in the first half of Chicago's 45-41 loss at Washington on Oct. 20. He had to be helped off the field, and an MRI revealed a torn groin muscle that was expected to sideline the quarterback for at least four weeks.
Cutler had other ideas.
The Bears had a bye week after the Washington loss, and Cutler watched while McCown led Chicago to a big 27-20 victory at Green Bay last Monday. Cutler then was cleared to play on Thursday and made the start against Detroit with the Lions, Bears and Packers all tied for the NFC North lead entering the day.
He insisted he was 100 per cent, but it was clear his groin was bothering him more and more as the game wore on. He grabbed his groin area and dropped to the ground after one third-quarter throw. He then popped right back up and remained in the game.
"It held up OK. It's all on the same leg so I think that was a problem," said Cutler, referring the groin and ankle injuries. "But the groin, you take the ankle out of the equation and I would have been fine, I think."
Cutler threw a 32-yard touchdown pass to Marshall on the first drive of the game. But he also had a pass tipped by Ndamukong Suh and grabbed by DeAndre Levy in the end zone for the linebacker's fifth interception.
NOTES: Levy began the day tied with seven other players for the NFL lead in interceptions. ... Each team played without a key defensive end. Detroit rookie Ziggy Ansah was out with a left ankle injury, and Chicago's Shea McClellin tweaked a hamstring during practice after he had three sacks in the victory at Green Bay. ... Lions RB Montell Owens left in the first quarter with a knee injury and did not return.
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Jay Cohen can be reached at http://www.twitter.com/jcohenap