Harper jokes that he's heard Ford say publicly he wants to be prime minister, a notion Harper says he clearly can't support.
But when it comes to the Toronto mayor's future, Harper says that's for the voters of that city to decide.
Harper says the Conservative government's position is clear: there are strict drugs laws in place, and no one should be buying or using illegal drugs, especially sitting politicians.
Ford's admission to having smoked crack cocaine "probably in one of my drunken stupors" made him a target of international ridicule and resulted in his being stripped of most of his mayoral powers.
The Conservative government has said little on the controversy, however — in part because the Tories have previously allied themselves with the popular, straight-talking mayor.
"I've heard Mr. Ford's statements to the effect that he would like to become prime minister of Canada; obviously this is not something I'm in favour of," Harper said at a news conference in Lac-Megantic, Que.
"In terms of his future in Toronto, that is for the residents of Toronto to decide."
As for Ford's admissions that he has smoked crack and purchased illegal drugs while sitting as mayor, Harper says, "we could never support the use or purchase of illegal drugs by anyone in political positions such as that."
Also on HuffPost