The Jan. 15 arrests are the result of a joint investigation between Alberta law enforcement teams and the United States Drug Enforcement Administration.
Charges against the trio include conspiracy to import cocaine, conspiracy to traffic cocaine, possession, trafficking, and possession of proceeds of crime.
Officials say the investigation began in Nevada in October 2012 when a traffic stop found 45 kilograms of cocaine packaged in vacuum-sealed bundles in a hidden compartment beneath a pickup truck.
Investigators believe the suspects are behind the drug-trafficking operation.
The three are believed to be a major cocaine distributor in southern Alberta and are alleged to have routinely used couriers to import cocaine from the southern U.S.
Charged are Christopher Mark Scher, who is 33; Michael Mirr Janecek, who is 37; and Steven Manuel Doporto, who is 31.
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