Firefighters rescued around 120 people after wintry conditions cut visibility on the roads and threatened to trap motorists inside of their cars.
The stranded travellers spent the night at either a fire hall in the township of Mulmur or at a nearby community centre, said Mulmur-Melancthon Fire Department Chief Jim Clayton.
He said he hopes firefighters will be able to return drivers to their vehicles after 11 a.m. on Saturday.
Tow trucks will assist the fire department by extracting cars from snow drifts.
Clayton said road closures remain in effect in parts of Dufferin and Grey counties.
Highway 10 is closed from Shelburne to Flesherton, while Highway 124 is closed from Shelburne to Singhampton, about 20 kilometres south of Collingwood.
“All the roads are very treacherous to drive right now,” Clayton said.