Police first discovered the bloody trail while canvassing an area of Mount Pleasant on Sunday morning.
They had been called to a home on East 6th Avenue near Brunswick Street after paramedics had found a seriously-wounded 70-year-old man. The man died in hospital hours later from what police called suspicious injuries.
Police officers cordoned off the home and the immediate area, and during the investigation found "a significant amount of blood" between Scotia Street and East. 6th Avenue and the south lane of East 6th Avenue and St. George Street.
But despite the suspicious nature of the man's death, police say they do not believe the trail of blood is related to the case, and they are hoping someone who knows something about the blood will come forward.
“At this point, it’s a mystery as to where the blood came from,” said VPD spokesperson Sgt. Randy Fincham.
“We are reaching out to the public to help us determine if someone was injured late Saturday night or early Sunday morning.”
Fincham said investigators are sending samples of the blood for DNA analysis, but it could take some time before results come back.
Map: Mount Pleasant blood trail