Buehrle (7-1) allowed two runs and six hits in six-plus innings. He walked a season-high five and struck out two. The left-hander came in with an AL-leading 1.91 ERA, but saw that rise to 2.04, the same as Detroit's Max Scherzer.
Bautista hit a three-run homer in the first inning and Lawrie, who returned to the lineup after missing six games with a sore right hamstring, added a two-run shot in the sixth as the Blue Jays avoided what would have been their first four-game sweep to the Angels.
Both homers came off Angels left-hander C.J. Wilson (4-3), who allowed five runs and six hits in six innings.
TIGERS 4, ORIOLES 1
BALTIMORE (AP) — Rick Porcello won his fifth straight start, and Detroit beat Baltimore in a duel between AL division leaders that included a benches-clearing confrontation.
After Ian Kinsler's two-run homer in the eighth made it 4-1, Orioles starter Bud Norris hit Torii Hunter in the ribcage with a pitch. Hunter yelled at Norris, and as he made his way toward first base, the Tigers outfielder moved slightly in the direction of the mound.
That caused both dugouts to empty, and relievers from both bullpens charged toward the infield. Order was quickly restored before anyone blatantly shoved each other, and no punches were thrown.
Norris (2-3) was ultimately ejected by plate umpire James Hoye. As the right-hander made his way toward the Baltimore dugout, he shouted once more at Hunter, who yelled back.
Joe Nathan got his eighth save, preserving the win for Porcello (6-1).
RANGERS 4, ASTROS 0
HOUSTON (AP) — Colby Lewis threw 5 2-3 shutout innings, and Adrian Beltre and Rougned Odor each homered to lead Texas over Houston.
Lewis (3-2) struck out a season-high eight and allowed seven hits to improve to 4-0 in his career at Minute Maid Park. The right-hander bounced back from a poor outing against Colorado on Wednesday where he allowed seven runs in less than four innings.
Beltre had two hits, including a two-run home run to left in the third. Odor had two hits, including a run-scoring single in the fourth and his first career home run in the sixth — a solo shot into the upper deck in right field — to make it 4-0. Prince Fielder also had two hits.
Brad Peacock (0-4) struck out a career-high 11 but allowed four runs on seven hits in six innings.
NEW YORK (AP) — Chris Young hit a tiebreaking homer in the eighth inning, Jenrry Mejia provided a jolt after his reluctant move to the bullpen and the previously punchless Mets went deep four times to rally past the Yankees in the Subway Series opener.
Curtis Granderson connected in his return to Yankee Stadium, and the Mets also got long balls from Eric Young Jr. and Travis d'Arnaud while overcoming a pair of three-run deficits. Lumbering first baseman Lucas Duda turned in two spectacular defensive plays, starting a game-ending double play with runners at the corners by making a diving stop of Brian McCann's sharp grounder.
Taking full advantage of the hitter-friendly confines across town, rather than the vast dimensions back home at Citi Field, the Mets hit four home runs in a game for the first time since May 3, 2013, in Atlanta, according to STATS.