While there are no restrictions on the amount of money that can be taken across the Canadian border, any amount over $10,000 must be reported.
The money, which was in several different currencies, was found distributed among several of the man’s pockets and in his carry-on case.
Canada Border Services Agency officers were conducting a routine outbound check on Sunday when they first spoke to the man.
According to officials, he declared he was carrying $20,000, prompting officers to do a more in-depth investigation to confirm.
When they found the rest of the cash, officials seized it as suspected proceeds of crime. They have not given any terms of release.
Officials say this was the largest seizure of suspected proceeds of crime by the CBSA in Edmonton, and the third largest in Alberta.
The largest seizure took place in Coutts in 2009 when border officers took more than $500,000 they found in a horse trailer.
The investigation into Sunday's seizure is ongoing.