Hortensia Rocha, 73, was last seen in the area of Weston Road and Coronado Court on Friday at 12 p.m.
She is described as white, five feet and one inch tall, with a medium build and grey hair. She was last seen driving a light grey, older model Chevy Tracker.
Police are concerned for her safety.
Anyone with information is asked to contact 31 Division at (416) 808-3100 or Crime Stoppers at 416-222-TIPS or www.222tips.com.