The family released a statement on Friday saying none of them ever saw abuse or any indication of inappropriate activity.
Matthew Sandusky said in Thursday's broadcast that his adopted father subjected him to a range of sexual abuse, including oral sex.
The statement is from Sandusky's wife, Dottie, and the couple's other five adopted children.
It says attacking Matthew will provoke him and they're worried about what he'll say about the family.
Jerry Sandusky is serving a prison term for sexual abuse of 10 boys. He has not been charged with abusing Matthew Sandusky.