The announcement will take place at the Seaman Hockey Resource Centre located at the MasterCard Centre in Toronto at 12:30 p.m. ET.
CBC News will live stream the conference, which will discuss managing mental illness, including education and identifying mental health concerns.
OHL commissioner David Branch and CMHA Ontario CEO Camille Quenneville will be on hand.
Earlier this year, the league had to cope with the death of Toronto native Terry Trafford, 20.
The Saginaw Spirit player was found dead in an SUV at a Wal-Mart store parking lot in Saginaw Township of Michigan.
It was found he died from asphyxiation, which police believe was self-inflicted.