RCMP say a minivan was travelling toward Fort St. John on Monday night when it failed to make a turn.
The van went into the ditch and rolled, ejecting both men inside.
Cpl. Dave Tyreman says RCMP, fire rescue and ambulance personnel attended the scene, but despite all lifesaving efforts the men were pronounced dead.
Police say the men were 27 and 47, but their names won't be released until their relatives have been notified.
The cause of the crash has not been determined, but RCMP haven't ruled out alcohol as a factor.