The deal kicks in for the 2015-16 season and lasts through the 2018-19 campaign, carrying an average annual salary of $5.75 million U.S.
"I believe in Marc-Andre Fleury, as the team does," said Rutherford. "He's won before and he will win again. We're very pleased to have him signed long term."
The 29-year-old Fleury is off to a good start in the 2014-15 season with a 7-2 record, 1.89 goals against average, and .931 save percentage.
According to reports, there is a limited no-trade clause in the contract.
The former No. 1 overall pick is 295-171-46 in 11 seasons. Fleury's 111 victories over the past four seasons are tops in the NHL.