Police found the man in a pool of his own blood shortly after receiving a call around 9:20 p.m. Friday.
The man, who police said was known to them, was found in front of an apartment building on Thessereault Street.
The man was transported to hospital. He died of his injuries overnight.
Investigators have set up a command post on Thessereault Street between 26th and 30th Avenue.
It is the 22nd homicide of the year in Montreal. At this time last year, Montreal had 25 homicides.