The bodies of a 22-year-old and a 23-year-old man were discovered inside the home in the 2100 block of Dorsey Avenue. Anahim Lake is about 400 kilometres north of Vancouver.
Cpl Dave Tyreman said the Emergency Response Team (ERT) and officers from Bella Coola, Alexis Creek and the North District Crime Unit were called in to assist.
Several suspects were arrested Saturday morning on a local roadway, police said, but didn't specify exactly where in Anahim Lake or how many were arrested.
Tyreman said it's believed those arrested and those killed all knew each other.
He said it's early in the investigation and more information may be released later.
MAP: Anahim Lake, B.C.