The MV Atlantic Erie, owned by Canadian Steamship Lines, was leaving Grand Entrée when it stalled on a sandbar.
The company says the incident will not have adverse consequences.
"There is no injury or pollution, and we've been told the outer shell suffered only minor damage," said John Sypnowich, CSL's chief legal officer.
The TSB has dispatched a team of investigators to look into the incident.
Conditions were windy at the time, says TSB spokesperson John Cottreau.
"No pollution is apparent now," said Cottreau, adding that no salt appears to have spilled.
Tow operations are still ongoing. No word how many crew are on board.
The Atlantic Erie had been chartered by Seleine Mines to carry the salt to Quebec.