The first reported crash involved two vehicles and occurred at about 11 p.m. on the eastbound ramp leading to Markham Road.
A 19-year-old Scarborough man faces two impaired-related charges.
Three-and-a-half hours later, police were called to a single-vehicle collision on the highway near Leslie Street.
A 37-year-old North York man was charged with impaired driving and failing to provide a breath sample.
At 3:17 a.m., police were called to the scene of a single-vehicle crash near Allen Road.
In this case, a 20-year-old Toronto man faces an impaired-related charge.
About 20 minutes after that collision, police responded to a single-vehicle crash near Bayview Avenue.
A 19-year-old Toronto man faces an impaired-related charge.
None of the allegations against the accused have been proven in court.