York Regional Police Staff Sgt. Rob Bentham said a man was walking on Hwy 11, just south of Bradford, when he was struck just before 6 a.m.
"It appears that two vehicles struck this pedestrian," Bentham said.
The man, whose identity was not released, was pronounced dead on the scene.
Hwy. 11 will remain closed in the area for several hours this morning while investigators try to piece together what happened.
There were two more fatal pedestrian collisions last night.
An 80-year-old man died in hospital Thursday morning after being struck by an SUV on Millwick Drive, near the intersection of Islington and Steeles, around 7:30 p.m. last night.
And a 61-year-old woman was also killed after she was hit by a truck near the Markham Rd. and Finch Ave. E. around 4:40 p.m.
Police said the woman was pronounced dead at the scene.
The driver involved in the collision remained at the scene and is co-operating with investigators, police said.
Woman seriously injured, driver sought
Toronto police are also searching for a driver after a 25-year-old pedestrian was seriously injured in a two-car collision.
Two vehicles collided around 7 p.m. near Seneca College's Newnham Campus at Don Mills Rd. and Finch Ave. E. and one left the road and struck the woman, police in 33 Division said.
The woman suffered life-threatening injuries.
One of the drivers in the collision failed to remain at the scene.
Police are urging anyone who witnessed the collision to contact them.