The couple that owns the house in the city's northwest had rented it out using the popular accommodation website Airbnb.
Star King said when she and her husband returned after the April 24-27 weekend, the renters had destroyed their home — leaving behind biohazardous material, furniture smeared with mayonnaise, floors buckling with pools of liquor and toilets plugged with condoms.
Police said they received several noise complaints about the house over the weekend.
Officers returned on the Monday after the homeowners asked for police assistance in getting people to leave.
Investigators are trying to identify suspects in relation to the credit card fraud through CCTV images, police said.
Police are also asking for people who were in the house while it was being vandalized to come forward and tell investigators who is responsible.
Police said an original damage estimate of between $50,000 and $75,000 has since climbed to about $150,000.
King said it could take a restoration company months to repair the house.
Airbnb offered the King family a free place to stay in the meantime.
The company is also covering the costs of repair and restoration of the house under its insurance, which provides up to $1 million "to eligible properties in the rare event of guest damages, which are not resolved directly with the guest."
Police are still searching for the man who originally rented the house and could charge him with mischief to property over $5,000.